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It's probably just an illusion, but I seem to be getting targeted spam lately.
How targeted spam might work: A crawler goes out and indexes an email and context. It then uses the context to generate a relevant spam title and keyword text that can then be matched to relevant messages from a database of client advertisements. The filter-defeating cocktail is then shuttled out to unwilling recipients across the web.
This is horrible. It's like adsense for spam.